CENSE

About CENSE

Center for Experimental Neurosciense (CENSE) at the Department of Neurosurgery and the Danish Neuroscience Center focuses on large animal research, specifically on the Göttingen minipig, for developing models of neurologic and psychiatric diseases. The brain of the minipig has a large degree of homology to the human brain and is sufficiently large for the use of human sized implant materials, neuromodulation devices, new medicine and stem cells for preclinical testing. CENSE has developed new anatomical atlases and MRI-guided stereotaxic equipment for placement of electrodes and neuromodulatory devices in the central nervous system, including the spinal cord. This includes the neurosurgical techniques as well as high TESLA MRI, PET and CT to test in vivo function. The group has also developed histopathology techniques for brain extraction and exact sectioning of brain sections in relation to scanning modalities and stereology purposes. Our procedures are performed according to GLP standards and conform to Aarhus University’s Animal Welfare Policy.

For further information: www.cense.dk

Visit CENSE

Research Focus

  • Translational neuroscience
  • Animal models of neurologic and psychiatric diseases
  • Neurosurgery
  • Neuromodulation
  • Pain research
  • Spinal cord lesion
  • Neuroanatomy  & neurobiology

Techniques/Infrastructure

  • Deep brain stimulation (DBS)
  • Spinal cord stimulation (SCS)
  • Stereotaxic neurosurgery and neuronavigation
  • Multicoil repetitive transcranial magnetic stimulation  (rTMS)
  • Neurostereology and neurohistology
  • Anaesthesia and surgical procedures in large animal models
  • Behavioural analysis in large animal models

Contact

Professor Jens Christian Hedemann Sørensen
Aarhus University Hospital
Department of Neurosurgery
Nørrebrogade 44, building 10, 5th floor
8000 Aarhus C
Denmark

jenssore@rm.dk
Tel. +45 7846 3465
Fax: +45 78463410

 

Key research/admin. personnel:

  • Professor Jens Christian H. Sørensen
  • Research Coordinator Anne Sofie Møller Andersen
  • Secretary Anja Kobberø
  • Postdoc Dariusz Orlowski
  • MD, PhD student Anders R. Korshøj
  • MD, PhD student Andreas N. Glud
  • Research Lab Tech Coordinator Lise M. Fitting
  • Research Lab Tech Trine W. Mikkelsen

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